Time and dose dependency of radiation-induced changes in tumor microvascular characteristics using contrast-enhanced magnetic resonance imaging: impact on the delivery of chemotherapeutic agents

Acad Radiol. 1996 Aug:3 Suppl 2:S347-8. doi: 10.1016/s1076-6332(96)80580-0.
No abstract available

MeSH terms

  • Adenocarcinoma / blood supply*
  • Adenocarcinoma / radiotherapy
  • Albumins / pharmacokinetics*
  • Animals
  • Antineoplastic Agents / pharmacokinetics
  • Antineoplastic Agents / pharmacology*
  • Capillary Permeability / physiology*
  • Capillary Permeability / radiation effects
  • Cisplatin / pharmacokinetics
  • Cisplatin / pharmacology*
  • Contrast Media / pharmacokinetics*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Gadolinium DTPA*
  • Magnetic Resonance Imaging*
  • Mammary Neoplasms, Experimental / blood supply*
  • Mammary Neoplasms, Experimental / radiotherapy
  • Microcirculation / physiopathology
  • Microcirculation / radiation effects
  • Organometallic Compounds / pharmacokinetics*
  • Pentetic Acid / analogs & derivatives*
  • Pentetic Acid / pharmacokinetics
  • Rats
  • Rats, Inbred F344

Substances

  • Albumins
  • Antineoplastic Agents
  • Contrast Media
  • Organometallic Compounds
  • albumin-(gadolinium-DTPA)
  • Pentetic Acid
  • Gadolinium DTPA
  • Cisplatin