ATP receptors in sickness, pain and death

A Brake; M Schumacher; D Julius

doi:10.1016/s1074-5521(96)90101-5

ATP receptors in sickness, pain and death

Chem Biol. 1996 Apr;3(4):229-32. doi: 10.1016/s1074-5521(96)90101-5.

Authors

A Brake¹, M Schumacher, D Julius

Affiliation

¹ Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA.

PMID: 8807849
DOI: 10.1016/s1074-5521(96)90101-5

Abstract

Extracellular ATP elicits biological responses ranging from cell death to synaptic transmission. Recent gene-cloning efforts have uncovered a family of cell-surface ATP receptors, which are potential targets for the development of novel drugs to treat airway and cardiovascular diseases, inflammation and pain.

Publication types

Review

MeSH terms

Adenosine Triphosphate / physiology
Animals
Apoptosis / physiology*
Cloning, Molecular
Inflammation / drug therapy
Pain / drug therapy
Pain / physiopathology*
Receptors, Purinergic P2 / genetics
Receptors, Purinergic P2 / physiology*

Substances

Receptors, Purinergic P2
Adenosine Triphosphate