Current clinical experience with nevirapine for HIV infection

Adv Exp Med Biol. 1996:394:299-304. doi: 10.1007/978-1-4757-9209-6_27.

Abstract

Nevirapine is a potent antiretroviral agent whose use, especially as monotherapy, may be limited by rapid onset of resistance as well as by hypersensitivity reactions. However, virologic features of nevirapine suggest that it may be useful in combination therapy with zidovudine or other antiretrovirals, including for patients infected with zidovudine-resistant strains HIV.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / adverse effects
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use*
  • Clinical Trials as Topic
  • HIV Infections / drug therapy*
  • HIV Infections / virology
  • HIV-1* / drug effects
  • Humans
  • Nevirapine
  • Pyridines / adverse effects
  • Pyridines / pharmacology
  • Pyridines / therapeutic use*

Substances

  • Antiviral Agents
  • Pyridines
  • Nevirapine