Evaluation of sulfa drugs against recombinant Pneumocystis carinii dihydropteroate synthetase and in vivo

J Eukaryot Microbiol. 1996 Sep-Oct;43(5):40S. doi: 10.1111/j.1550-7408.1996.tb04976.x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antifungal Agents / pharmacology*
  • Dihydropteroate Synthase / antagonists & inhibitors*
  • Enzyme Inhibitors / pharmacology*
  • Folic Acid / biosynthesis
  • Mice
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Pneumocystis / drug effects*
  • Pneumocystis / metabolism
  • Rats
  • Sulfamethoxypyridazine / pharmacology
  • Sulfanilamides / chemistry
  • Sulfanilamides / pharmacology*

Substances

  • Antifungal Agents
  • Enzyme Inhibitors
  • Sulfanilamides
  • Folic Acid
  • Dihydropteroate Synthase
  • Sulfamethoxypyridazine