Transcranial duplex monitoring discloses hemorrhagic complication following rt-PA thrombolysis

Acta Neurol Scand. 1996 Jan;93(1):61-3. doi: 10.1111/j.1600-0404.1996.tb00172.x.

Abstract

Introduction: Transcranial color-coded sonography (TCCS) allows imaging of basal cerebral arteries as well as brain parenchyma. It may therefore serve to monitor thrombolysis in acute stroke.

Case description: rt-PA thrombolysis was performed in a patient, suffering from paradoxical embolism causing MCA occlusion. Hemorrhage immediately after completion of rt-PA infusion as well as delayed MCA recanalization could be monitored by TCCS.

Conclusion: TCCS is useful to improve monitoring and safety of systemic thrombolytic treatment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Flow Velocity / drug effects
  • Blood Flow Velocity / physiology
  • Cerebral Hemorrhage / chemically induced*
  • Cerebral Hemorrhage / diagnostic imaging
  • Humans
  • Intracranial Embolism and Thrombosis / diagnostic imaging
  • Intracranial Embolism and Thrombosis / therapy*
  • Male
  • Neurologic Examination / drug effects
  • Thrombolytic Therapy / adverse effects*
  • Tissue Plasminogen Activator / administration & dosage
  • Tissue Plasminogen Activator / adverse effects*
  • Ultrasonography, Doppler, Color
  • Ultrasonography, Doppler, Transcranial*
  • Weight-Bearing

Substances

  • Tissue Plasminogen Activator