Abstract
High doses of immunoglobulins (IVIG) may have beneficial effects in patients with autoimmune diseases. In this review several different mechanisms of action are discussed. These mechanisms include effects on the effector phase of the immune response, on the initial steps of the immune response and on the mixed lymphocytic reaction.
MeSH terms
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Antibody Formation / drug effects
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Autoimmune Diseases / drug therapy*
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Autoimmune Diseases / physiopathology
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Dose-Response Relationship, Drug
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Humans
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Immunity / drug effects
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Immunoglobulins, Intravenous / pharmacology
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In Vitro Techniques
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Lymphocyte Culture Test, Mixed
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Receptors, Fc / immunology
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Receptors, IgG / immunology
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T-Lymphocytes, Helper-Inducer / immunology
Substances
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Immunoglobulins, Intravenous
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Receptors, Fc
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Receptors, IgG