A patient with symptomatic pliable mitral stenosis and a significant lesion in the right coronary artery underwent combined interventional procedures during a single session. After an uneventful transseptal puncture that allowed full anticoagulation with heparin, a percutaneous transluminal coronary angioplasty was performed, yielding an unsatisfactory result and necessitating stent implantation. Thereafter, mitral stenosis was relieved by percutaneous balloon valvotomy. The specific problems arising from the combination of the two procedures are discussed.