Objective: We examined the soluble CD23 (sCD23) molecules in sera and saliva from patients with Sjögren's syndrome.
Methods: The determination of sCD23 and other soluble molecules were made by the enzyme-linked immunosorbent assay.
Results: The amounts of sCD23 in the sera/saliva were significantly increased in the patients compared to the controls and the levels were significantly correlated with sialoectasis.
Conclusion: The findings suggest that increased sCD23 molecules in saliva from patients with Sjögren's syndrome may reflect active sialoectasis.