Electron transfer from cytochrome b5 to cytochrome c

J Bioenerg Biomembr. 1995 Jun;27(3):331-40. doi: 10.1007/BF02110102.

Abstract

The reaction of cytochrome b5 with cytochrome c has become a very prominent system for investigating fundamental questions regarding interprotein electron transfer. One of the first computer modeling studies of electron transfer and protein/protein interaction was reported using this system. Subsequently, numerous studies focused on the experimental determination of the features which control protein/protein interactions. Kinetic measurements of the intracomplex electron transfer reaction have only appeared in the last 10 years. The current review will provide a summary of the kinetic measurements and a critical assessment of the interpretation of these experiments.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Binding Sites
  • Computer Simulation
  • Cytochrome c Group / chemistry*
  • Cytochrome c Group / metabolism*
  • Cytochromes b5 / chemistry*
  • Cytochromes b5 / metabolism*
  • Electron Transport
  • Kinetics
  • Models, Molecular
  • Protein Structure, Secondary*
  • Thermodynamics

Substances

  • Cytochrome c Group
  • Cytochromes b5