Abstract
We performed the locoregional injection of OK-432/fibrinogen/thrombin to unresectable hepatic tumors metastasized from colorectal cancers, which were hardly controlled by arterial infusion chemotherapy. CEA was markedly decreased following this treatment, although abdominal CT did not show a significant reduction of tumor mass. This immuno-injection therapy may be a choice of treatment for metastatic liver tumors, refractory to treatment by conventional chemotherapy.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Antineoplastic Agents / administration & dosage*
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Carcinoembryonic Antigen / blood
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Colorectal Neoplasms / pathology
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Drug Administration Schedule
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Drug Therapy, Combination
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Female
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Fibrinogen / administration & dosage*
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Humans
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Injections, Intralesional
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Liver Neoplasms / immunology
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Liver Neoplasms / secondary
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Liver Neoplasms / therapy*
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Male
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Middle Aged
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Picibanil / administration & dosage*
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Thrombin / administration & dosage*
Substances
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Antineoplastic Agents
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Carcinoembryonic Antigen
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Picibanil
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Fibrinogen
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Thrombin