beta-Thalassemia mutation at -90C-->T impairs the interaction of the proximal CACCC box with both erythroid and nonerythroid factors

Blood. 1996 Oct 15;88(8):3248-9.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Chloramphenicol O-Acetyltransferase / biosynthesis
  • Chloramphenicol O-Acetyltransferase / genetics
  • DNA / genetics
  • DNA / metabolism*
  • DNA-Binding Proteins / metabolism*
  • Erythroid Precursor Cells / metabolism
  • Gene Expression Regulation*
  • Genes, Reporter
  • Globins / biosynthesis
  • Globins / genetics*
  • HeLa Cells
  • Humans
  • Kruppel-Like Transcription Factors
  • Organ Specificity
  • Point Mutation*
  • Promoter Regions, Genetic*
  • Protein Binding
  • Recombinant Fusion Proteins / biosynthesis
  • Recombinant Fusion Proteins / genetics
  • Transcription Factors / metabolism*
  • Transcription, Genetic*
  • Zinc Fingers
  • beta-Thalassemia / ethnology
  • beta-Thalassemia / genetics*

Substances

  • DNA-Binding Proteins
  • Kruppel-Like Transcription Factors
  • Recombinant Fusion Proteins
  • Transcription Factors
  • erythroid Kruppel-like factor
  • Globins
  • DNA
  • Chloramphenicol O-Acetyltransferase