Procorticotrophin releasing hormone is endoproteolytically processed by the prohormone convertase PC2 but not by PC1 within stably transfected CHO-K1 cells

Biochem Soc Trans. 1996 Aug;24(3):497S. doi: 10.1042/bst024497s.

Authors

M J Perone¹, I Ahmed, E A Linton, M G Castro

Affiliation

¹ Dept. of Medicine, University of Manchester.

PMID: 8879041
DOI: 10.1042/bst024497s

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aspartic Acid Endopeptidases / genetics
Aspartic Acid Endopeptidases / metabolism*
CHO Cells
Corticotropin-Releasing Hormone / metabolism*
Cricetinae
Immunohistochemistry
Proprotein Convertase 2
Proprotein Convertases
Protein Precursors / metabolism*
Protein Processing, Post-Translational
Subtilisins / genetics
Subtilisins / metabolism*
Transfection

Substances

Protein Precursors
pro-corticotropin releasing hormone
Corticotropin-Releasing Hormone
Proprotein Convertases
Subtilisins
Proprotein Convertase 2
Aspartic Acid Endopeptidases