Sequence analysis of pre-S/S gene of hepatitis B virus strains of genotypes A, D, and F isolated in Brazil

Arch Virol. 1996;141(9):1767-73. doi: 10.1007/BF01718299.

Abstract

The nucleotide sequences of pre-S/S gene of nine hepatitis B virus strains (3 adw2, 3 ayw2, and 3 ayw 3) and of pre-S region of two adw4 isolates from Rio de Janeiro, Brazil, were determined. Phylogenetic analysis allowed to classify these strains into three genotypes, A, D and F, reflecting the diverse origin of the population. However, strains belonging to a same genotype were separated by a short evolutionary distance. The presence of aminoacid mutations into Pre-S region not found in hepatitis B viruses isolated in other parts of the world is described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Brazil
  • Evolution, Molecular
  • Gene Products, env / chemistry*
  • Gene Products, env / genetics
  • Genes, env*
  • Genotype
  • Hepatitis B virus / classification*
  • Hepatitis B virus / genetics*
  • Hepatitis B virus / isolation & purification
  • Humans
  • Molecular Sequence Data
  • Mutation
  • Phylogeny*
  • Polymerase Chain Reaction
  • Sequence Homology, Amino Acid

Substances

  • Gene Products, env

Associated data

  • GENBANK/U55220
  • GENBANK/U55221
  • GENBANK/U55222
  • GENBANK/U55223
  • GENBANK/U55224
  • GENBANK/U55225
  • GENBANK/U55226
  • GENBANK/U55227
  • GENBANK/U55228
  • GENBANK/U55229
  • GENBANK/U55230