Isolation and mapping of the human glycoprotein M6 gene (GPM6A) to 4q33-->q34

Cytogenet Cell Genet. 1996;74(1-2):138-9. doi: 10.1159/000134401.

Abstract

We have isolated a human cDNA that is highly homologous to the murine gene (Gpm6) encoding a membrane glycoprotein, M6. The human gene (GPM6A) contains an open reading frame of 834 nucleotides encoding a peptide of 278 amino acids. Northern-blot analysis revealed specific expression in human brain. We assigned the GPM6A locus to chromosome bands 4q33-->q34 by radiation hybrid mapping.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Blotting, Northern
  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 4*
  • Humans
  • Membrane Glycoproteins / genetics*
  • Molecular Sequence Data
  • Nerve Tissue Proteins / genetics*
  • RNA, Messenger / analysis

Substances

  • GPM6A protein, human
  • Membrane Glycoproteins
  • Nerve Tissue Proteins
  • RNA, Messenger

Associated data

  • GENBANK/D49958