Abstract
We report a case of an epileptic pregnant woman at 20 weeks of gestation treated with carbamazepine, whose fetus was affected by major malformations probably due to the drug teratogenicity. After a therapeutic abortion minor malformations were also found. After seven months the patient was pregnant again, at 14 weeks of gestation she aborted spontaneously a fetus with no malformations. During this pregnancy the patient took a reduced dosage of carbamazepine.
MeSH terms
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Abnormalities, Drug-Induced / diagnostic imaging
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Abnormalities, Drug-Induced / etiology*
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Abortion, Eugenic
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Adult
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Anticonvulsants / administration & dosage
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Anticonvulsants / adverse effects*
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Carbamazepine / administration & dosage
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Carbamazepine / adverse effects*
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Epilepsy / diagnostic imaging
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Epilepsy / drug therapy*
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Female
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Humans
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Pregnancy
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Pregnancy Complications / diagnostic imaging
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Pregnancy Complications / drug therapy*
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Pregnancy Trimester, Second
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Ultrasonography, Prenatal
Substances
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Anticonvulsants
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Carbamazepine