Abstract
The development of a graft-versus-host reaction after allogeneic hematopoietic stem cell transplantation is an important determinant of the transplant outcome. A better understanding and improved management of the graft-versus-host reaction should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemia effect and to decrease the incidence of leukemic relapse after transplantation.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Cell Adhesion Molecules / immunology
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Cytokines / immunology
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Disease Models, Animal
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Graft vs Host Disease / etiology
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Graft vs Host Disease / immunology*
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Graft vs Host Disease / prevention & control
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Graft vs Host Reaction*
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HLA Antigens / genetics
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Hematopoietic Stem Cell Transplantation* / adverse effects
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Humans
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Immunogenetics
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Leukemia / immunology
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Leukemia / therapy
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T-Lymphocytes / immunology
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Transplantation, Homologous
Substances
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Cell Adhesion Molecules
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Cytokines
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HLA Antigens