Treatment of osteomyelitis in the diabetic foot. Contribution of conservative surgery

Diabetes Care. 1996 Nov;19(11):1257-60. doi: 10.2337/diacare.19.11.1257.

Abstract

Objective: To compare the duration of healing of foot ulcers with osteomyelitis in diabetic patients treated by medical treatment versus medical treatment associated with conservative orthopedic surgery.

Research design and methods: We entered into the study 67 diabetic patients who had a foot ulcer with osteomyelitis without ischemia requiring a peripheral arterial reconstruction. Thirty-two diabetic patients were included in a first historic group from 1986 to 1993, treated by antibiotic therapy, offloading, and wound care. Thirty-two patients were included from September 1993 to March 1995, treated by the same medical treatment and conservative orthopedic surgery.

Results: The healing rate was 57% in the group treated by the medical treatment alone versus 78% in the surgical group (P < 0.008). The duration of healing was 462 +/- 98 days versus 181 +/- 30 days (P < 0.008).

Conclusions: Conservative surgery contributes to an increase in the healing rate of foot ulcers with osteomyelitis compared with a medical treatment alone.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Diabetes Mellitus, Type 1 / physiopathology
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetic Foot / complications*
  • Diabetic Foot / therapy*
  • Female
  • Humans
  • Male
  • Metatarsus / surgery
  • Middle Aged
  • Osteomyelitis / surgery*
  • Osteomyelitis / therapy
  • Retrospective Studies
  • Toes / surgery
  • Treatment Outcome
  • Wound Healing

Substances

  • Anti-Bacterial Agents