Fibrolamellar hepatocellular carcinoma responsive to platinum-based combination chemotherapy

Clin Oncol (R Coll Radiol). 1996;8(5):331-3. doi: 10.1016/s0936-6555(05)80724-1.

Abstract

A patient with advanced unresectable fibrolamellar hepatocellular carcinoma is reported, who was treated with cisplatinum, epirubicin and 5-fluorouracil combination chemotherapy. Tumour regression was achieved, enabling major debulking surgery to be performed. The patient remains in clinical remission 11 months after completing therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biopsy
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / drug therapy*
  • Carcinoma, Hepatocellular / surgery
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Epirubicin / administration & dosage
  • Fluorouracil / administration & dosage
  • Humans
  • Leucovorin / administration & dosage
  • Liver / pathology
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / surgery
  • Male
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Epirubicin
  • Cisplatin
  • Leucovorin
  • Fluorouracil

Supplementary concepts

  • FLEP protocol