Successful treatment on an out-patient basis of a patient with Down's syndrome and disseminated testicular seminoma

S Sleijfer; H S Koops; W T van der Graaf

doi:10.1016/0300-2977(95)00058-5

Successful treatment on an out-patient basis of a patient with Down's syndrome and disseminated testicular seminoma

Neth J Med. 1996 Mar;48(3):89-91. doi: 10.1016/0300-2977(95)00058-5.

Authors

S Sleijfer¹, H S Koops, W T van der Graaf

Affiliation

¹ Department of Internal Medicine, University Hospital, Groningen, Netherlands.

PMID: 8935748
DOI: 10.1016/0300-2977(95)00058-5

Abstract

Due to a high incidence of undescended testicles, patients with Down's syndrome have an increased risk of testicular cancer. The treatment of these patients with the successful cisplatin-containing regimens, which are however toxic and require hospitalization, can cause several problems. We present a patient with Down's syndrome suffering from a disseminated seminomatous tumour of the testis who has been successfully treated with combination chemotherapy on an out-patient basis.

Publication types

Case Reports

MeSH terms

Adult
Ambulatory Care*
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Carboplatin / administration & dosage
Carboplatin / adverse effects
Cryptorchidism / complications
Cryptorchidism / genetics
Cyclophosphamide / administration & dosage
Cyclophosphamide / adverse effects
Down Syndrome / complications*
Down Syndrome / genetics
Humans
Male
Risk Factors
Seminoma / drug therapy*
Seminoma / genetics
Testicular Neoplasms / drug therapy*
Testicular Neoplasms / genetics
Vincristine / administration & dosage
Vincristine / adverse effects

Substances

Vincristine
Cyclophosphamide
Carboplatin