Abstract
Recent molecular models and crystallographic analysis of the major protein of peripheral myelin have provided new insights into the molecular basis of membrane adhesion in myelin. These studies have proved useful in understanding the molecular basis of clinical phenotypes in certain demyelinating neuropathies.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Crystallography, X-Ray
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Demyelinating Diseases / etiology*
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Mice
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Models, Molecular
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Myelin P0 Protein / chemistry*
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Myelin Sheath / ultrastructure*
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Nerve Fibers / ultrastructure*
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Protein Conformation
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Rabbits