In the analysis of medical records of 7 patients in one neurological service, different clinical aspects of cryptococcal meningitis such as diagnostic criteria, risk factors, clinical features, CSF features, and therapeutical features are reviewed. The finding on India ink preparation of Cryptococcus neoformans in the cerebrospinal fluid and the distinguishing clinical features of a chronic meningitis were the only diagnostic criteria in these 7 cases. Treatment with amphotericine B was the sole mean in the management of these cases. There were only two cases of complete cure, and 5 patients deceased. Intravenous associated with intrathecally injection of amphotericine B has been carried out in the two successfully treated patients.