Abstract
A previously healthy 2 1/2-year-old girl developed status epilepticus followed by cortical blindness during intravenous N-acetylcysteine therapy for paracetamol ingestion. The child's vision was almost completely recovered during the 18 months follow-up period. We assume that the cortical blindness was a postictal sequela after prolonged seizure episode, most probably due to respiratory depression induced by N-acetylcysteine.
MeSH terms
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Acetaminophen / poisoning*
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Acetylcysteine / adverse effects*
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Analgesics, Non-Narcotic / poisoning*
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Anticonvulsants / therapeutic use
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Blindness / chemically induced*
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Child, Preschool
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Female
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Free Radical Scavengers / adverse effects*
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Humans
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Infusions, Intravenous
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Phenobarbital / therapeutic use
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Status Epilepticus / chemically induced*
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Status Epilepticus / drug therapy
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Status Epilepticus / physiopathology
Substances
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Analgesics, Non-Narcotic
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Anticonvulsants
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Free Radical Scavengers
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Acetaminophen
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Acetylcysteine
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Phenobarbital