C-reactive protein as an indicator of complications in bacterial meningitis

Indian Pediatr. 1996 May;33(5):373-6.

Abstract

Objective: To determine the value of serum C-reactive protein (CRP) estimation in the follow-up of bacterial meningitis (BM).

Design: Longitudinal follow-up.

Setting: Urban hospital.

Methods: Sequential serum CRP estimation was done in 50 healthy children and in 100 children with BM. Serial serum CRP value was correlated with the clinical picture in BM.

Results: Serial serum CRP in 14 patients with complicated BM was significantly different than the 72 uncomplicated BM cases.

Conclusions: Serial determination of serum CRP may be a cheap, simple and reliable prognostic indicator in BM.

MeSH terms

  • Bacteria / isolation & purification*
  • Biomarkers / analysis*
  • Biomarkers / blood
  • C-Reactive Protein / analysis*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Longitudinal Studies
  • Male
  • Meningitis, Bacterial / complications*
  • Meningitis, Bacterial / diagnosis
  • Prognosis
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Biomarkers
  • C-Reactive Protein