Pulse diagnosis were performed on 85 patients who came to the hospital for liver and gall-bladder problems. Correlation between liver tests, which include T-Bil, D-Bil, SGOT, SGPT, ZTT, Alp, gamma-GT, Cho, Alb, and ultra sound scanning, and pulse diagnosis were analyzed. 77 out of 85 subjects showed abnormal liver tests. We used the following 5 criteria for pulse diagnosis as liver abnormality to test the correlation: (1) C1 > or = 3+ and C1 + C4 > or = 4+ or C1 + C6 > or = 4 (in intensity); (2) C1 < or = 3 (in intensity); (3) C6 > or = 3 and C1 + C6 > or = 4 (in intensity); (4) C6 < or = -2 (in intensity) and C6 < or = -2 (in the phase) and (5) C1 > or = 2 C3 < or = -2 (in intensity) or C3 < or = -2 (in the phase). For C1 (liver) every 5% above normal was given one "+," every 5% below normal was given one "-." For C3 (spleen), C4 (lung), C6 (gall-bladder), every 10% above normal was given one "+,", every 10% below normal was given one "-." For the phase, every 10% delay in the traveling speed was given one "-." When considering only the "+" and "-" states and neglecting the quantity of "+" and "-," there are 2(11) (from intensity) x 2(11) (from phase), which equal 2048 x 2048 possible states in the pulse analysis. We considered only 5 criteria for liver abnormality; the correlation was still very high, p < 0.0002, kappa = 0.64. It strongly suggests that meridian theory and pulse diagnosis have physiological and pathological importance.