Fusaricide, a new cytotoxic N-hydroxypyridone from Fusarium sp

J Nat Prod. 1996 Dec;59(12):1151-3. doi: 10.1021/np960521t.

Abstract

A new cytotoxic N-hydroxypyridone, fusaricide (1), was isolated from a Fusarium sp. Its structure was solved by X-ray diffraction and spectroscopic analyses.

MeSH terms

  • Antifungal Agents / pharmacology
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Benzopyrans / isolation & purification*
  • Benzopyrans / pharmacology
  • Crystallography, X-Ray
  • Fungi / drug effects
  • Fusarium / chemistry*
  • Gene Expression Regulation, Viral / drug effects
  • Microbial Sensitivity Tests
  • Pyridones / isolation & purification*
  • Pyridones / pharmacology
  • Tumor Cells, Cultured
  • Virion / drug effects

Substances

  • Antifungal Agents
  • Antineoplastic Agents
  • Benzopyrans
  • Pyridones
  • fusaricide