Fibrolipocalcareous myopathy also known as Mattioli-Foggia and Raso Disease was observed first time in 1945. They described clinical, anatomopathologic and radiological Bigliardi aspects. At present the published cases are more than forty. We have pointed out our attention on the published cases. We believe, regard to histopathological and whole clinical data, that this disease could be considered as a) the outcome of a vascular hamartoma; or b) the consequence of a "mesoblastic phacomatosis".