Structural requirements of chiral clofibric acid analogs for activation of the rat peroxisome proliferator-activated receptor alpha

Ann N Y Acad Sci. 1996 Dec 27:804:713-5. doi: 10.1111/j.1749-6632.1996.tb18677.x.
No abstract available

MeSH terms

  • Acyl-CoA Oxidase
  • Animals
  • Cell Line
  • Chlorocebus aethiops
  • Clofibric Acid / analogs & derivatives
  • Clofibric Acid / chemistry*
  • Gene Expression Regulation, Enzymologic / drug effects
  • Microbodies / drug effects*
  • Microbodies / enzymology
  • Oxidoreductases / genetics
  • Rats
  • Receptors, Cytoplasmic and Nuclear / genetics*
  • Stereoisomerism
  • Structure-Activity Relationship
  • Transcription Factors / genetics*

Substances

  • Receptors, Cytoplasmic and Nuclear
  • Transcription Factors
  • Clofibric Acid
  • Oxidoreductases
  • Acyl-CoA Oxidase