Different dental appliances have been recommended in the treatment of snoring. The aim of the present study was to compare three different dental appliances regarding patient tolerance and the effect of snoring. Fifteen consecutive snorers were randomly selected to treatment with either a mandibular advancement device (activator), a soft-palate lifter or a mouth-shield. The activator satisfactorily reduced snoring in four out of five patients. At four-year follow-up, two patients had discontinued the treatment, one due to craniomandibular disorder. The soft-palate lifter had insufficient effect on snoring in four out of five patients. The results suggest that the activator has a satisfactory tolerance and effect on snoring, while the soft-palate lifter and the mouth-shield are ineffective in the treatment of snoring.