The authors present an account on an uncommon case when damage of visual functions of a patient were due to two independent cause: amiodarone neuropathy of the optic nerve (ANO) and an intracranial tumour-a craniopharyngioma. Effective treatment of both diseases achieved marked improvement of visual functions. The authors want to draw attention to the fact that one disease which theoretically would be sufficient to explain impaired vision, is not necessarily the only disease from which the patient suffers. Comprehensive examination is always essential.