Abstract
We report a case of prostatic cancer in which transformation from adenocarcinoma into small cell carcinoma was demonstrated both by histology and immunohistochemistry. This phenomenon supports the hypothesis that small cell carcinoma of the prostate originates from multipotential prostatic epithelial cells.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenocarcinoma / diagnosis
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Adenocarcinoma / pathology*
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Adenocarcinoma / therapy
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Biopsy, Needle
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Carcinoma, Small Cell / diagnosis
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Carcinoma, Small Cell / pathology*
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Carcinoma, Small Cell / therapy
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Cell Transformation, Neoplastic / pathology*
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Combined Modality Therapy
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Epithelium / pathology
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Fatal Outcome
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Humans
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Male
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Middle Aged
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Prostate / pathology
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Prostate-Specific Antigen / blood*
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Prostatic Neoplasms / diagnosis
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Prostatic Neoplasms / pathology*
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Prostatic Neoplasms / therapy
Substances
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Prostate-Specific Antigen