Abstract
Recently, a method for transcranial magnetic stimulation (TMS) of the brain has been developed. Thus, it is possible to explore neurochemical and behavioral effects of TMS in rats. Repeated TMS (9 days) reduced beta-adrenergic receptor binding in cortex, as does electroconvulsive shock (ECS) and other antidepressant treatments. Thus TMS appears to be a potential antidepressive treatment.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adrenergic beta-Agonists / pharmacokinetics
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Animals
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Cerebral Cortex / metabolism
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Cerebral Cortex / radiation effects*
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Down-Regulation / radiation effects
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Electromagnetic Fields*
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Hippocampus / metabolism
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Hippocampus / radiation effects
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Male
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Membranes / metabolism
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Propanolamines / pharmacokinetics
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Rats
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Rats, Sprague-Dawley
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Receptors, Adrenergic, beta / radiation effects*
Substances
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Adrenergic beta-Agonists
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Propanolamines
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Receptors, Adrenergic, beta
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CGP 12177