Design of nucleoside analog inhibitors of herpesvirus polymerases

Methods Enzymol. 1996:275:425-40. doi: 10.1016/s0076-6879(96)75025-5.

Authors

E J Prisbe¹, M S Chen

Affiliation

¹ Gilead Sciences, Inc., Foster City, California 94404, USA.

PMID: 9026653
DOI: 10.1016/s0076-6879(96)75025-5

No abstract available

MeSH terms

Antiviral Agents / chemistry
Antiviral Agents / pharmacology*
Drug Design
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Humans
Kinetics
Molecular Structure
Nucleic Acid Synthesis Inhibitors*
Nucleosides / chemistry
Nucleosides / pharmacology*
Organophosphonates / chemistry
Organophosphonates / pharmacology
Simplexvirus / drug effects
Simplexvirus / enzymology*
Structure-Activity Relationship

Substances

Antiviral Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Nucleosides
Organophosphonates