An information system for chemical safety has been developed on the National Institute of Health Sciences (NIHS) Information and Computing Infrastructure. The system is based on client server systems on the local area network (LAN) connected to the Internet. A wide range of safety information for chemicals including foods, food additives, household goods, industrial chemicals and environmental pollutants were collected and put on the World Wide Web (WWW) server and the database management system, Sybase. In addition to original information contents, the System has links to many useful Web sites so that it functions as a global hub for chemical safety information.