Synthesis, chemical solvolytic stability and preliminary biological evaluation of (+/-)-N-Boc-CPzI: a pyrazole analog of the left-hand segment of the antitumor agent CC-1065

Anticancer Drug Des. 1997 Jan;12(1):67-74.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibiotics, Antineoplastic / chemical synthesis*
  • Antibiotics, Antineoplastic / pharmacology
  • Drug Screening Assays, Antitumor
  • Duocarmycins
  • Indoles*
  • Leucomycins / chemistry*
  • Leukemia L1210 / drug therapy
  • Pyrazoles / chemical synthesis*
  • Pyrazoles / pharmacology

Substances

  • Antibiotics, Antineoplastic
  • Duocarmycins
  • Indoles
  • Leucomycins
  • N-Boc-CPzI
  • Pyrazoles
  • CC 1065