Evaluation of MRI-MEG/EEG co-registration strategies using Monte Carlo simulation

Electroencephalogr Clin Neurophysiol. 1997 Feb;102(2):81-5. doi: 10.1016/s0921-884x(96)96570-4.

Abstract

We present a Monte Carlo analysis method for evaluating MRI-MEG/EEG co-registration techniques. The method estimates the error in co-registration as a function of position within the brain. Using this analysis technique, we demonstrate the limitations of conventional head-based fiducial point methods, and propose a new strategy utilising a dental bite-bar incorporating accurately machined fiducial markers. Results presented demonstrate the improved accuracy of MEG/EEG to MRI co-registration using the bite-bar.

MeSH terms

  • Brain / physiology*
  • Electroencephalography*
  • Humans
  • Magnetic Resonance Imaging*
  • Magnetoencephalography*
  • Monte Carlo Method*
  • Reference Standards