Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine

Int J Dev Biol. 1996:Suppl 1:291S-292S.

Authors

N Ubeda¹, E Alonso, J C Martín-Rodríguez, G Varela-Moreiras, J Puerta, J Pérez-Miguelsanz

Affiliation

¹ Departamento de Ciencias Morfológicas I, Facultad de Medicina, Universidad Complutense, Madrid, Spain.

PMID: 9087803

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Abnormalities, Drug-Induced / prevention & control*
Animals
Anticonvulsants / antagonists & inhibitors*
Anticonvulsants / toxicity*
Bone and Bones / abnormalities
Female
Fetus / drug effects
Fetus / metabolism
Leucovorin / administration & dosage*
Leucovorin / metabolism
Liver / drug effects
Liver / metabolism
Methionine / metabolism
Methylation
Neural Tube Defects / prevention & control
Pregnancy
Rats
Rats, Wistar
S-Adenosylmethionine / administration & dosage*
S-Adenosylmethionine / metabolism
Valproic Acid / antagonists & inhibitors*
Valproic Acid / toxicity*

Substances

Anticonvulsants
Valproic Acid
S-Adenosylmethionine
Methionine
Leucovorin