Abstract
SpHox8 is the paralog group 8 Hox gene of Strongylocentrotus purpuratus. This identification follows from an analysis of the sequence of the complete open reading frame of a late-gastrula-stage cDNA clone; from direct linkage to adjacent Hox genes in a fosmid contig; and from blot hybridizations carried out on pulse field gel electrophoretic separations. SpHox8 is a single-copy gene, and there is only one Hox gene cluster per genome in S. purpuratus.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular
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Conserved Sequence
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DNA Primers
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DNA, Complementary
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Genes, Homeobox*
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Genetic Linkage
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Homeodomain Proteins / chemistry
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Homeodomain Proteins / genetics*
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Molecular Sequence Data
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Multigene Family*
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Recombinant Proteins / chemistry
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Sea Urchins / genetics*
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Sequence Homology, Amino Acid
Substances
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DNA Primers
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DNA, Complementary
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Homeodomain Proteins
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Recombinant Proteins
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SpHox8 protein, Strongylocentrotus purpuratus