Therapeutic approach of immotile cilia syndrome by intracytoplasmic sperm injection: a case report

Fertil Steril. 1997 Mar;67(3):562-5. doi: 10.1016/s0015-0282(97)80087-8.

Abstract

Objective: To present a case of immotile cilia syndrome, a very rare cause of male infertility and to evaluate the role of the recently suggested treatment by intracytoplasmic sperm injection (ICSI).

Design: Case report.

Setting: Tertiary-care academic hospital.

Patient(s): One man with immotile cilia syndrome, showing no motile spermatozoa despite normal morphology and viability.

Intervention(s): The patient's partner underwent two cycles with IVF of the oocytes achieved by ICSI.

Main outcome measure(s): Evaluation of ICSI procedure in cases of immotile cilia syndrome.

Result(s): Thirty-three percent of the oocytes were fertilized and subsequently divided enabling ET in both cycles.

Conclusion(s): Intracytoplasmic sperm injection seems to represent a promising approach to the problem of infertility in men with immotile cilia syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dyneins / deficiency
  • Fertilization in Vitro / methods*
  • Humans
  • Infertility, Male / etiology*
  • Male
  • Microinjections
  • Microscopy, Electron
  • Oocytes
  • Ovulation Induction / methods
  • Sperm Motility*
  • Sperm Tail / pathology
  • Sperm Tail / ultrastructure
  • Spermatozoa / abnormalities*
  • Spermatozoa / pathology
  • Spermatozoa / ultrastructure
  • Syndrome

Substances

  • Dyneins