Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome

Gene. 1997 Mar 18;187(2):179-84. doi: 10.1016/s0378-1119(96)00743-3.

Abstract

The positioning of Expressed Sequence Tags (ESTs) constitutes an important step towards a functional map of the human genome, including candidate genes for human genetic disorders that have been localized by linkage analysis. We localized 59 ESTs on the human X chromosome, including 44 derived from infant brain and 15 from adult muscle cDNA libraries. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Chromosome Mapping*
  • Cricetinae
  • DNA, Complementary*
  • Gene Expression Regulation
  • Genetic Markers
  • Humans
  • Hybrid Cells
  • Mice
  • Molecular Sequence Data
  • Repetitive Sequences, Nucleic Acid
  • X Chromosome*

Substances

  • DNA, Complementary
  • Genetic Markers

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