The purpose of the study was to examine the protective role of lyophilic dairy products bulgaricum and biostim with active bacteria lactic acid strain. Protective effect was determined as a phagocytosis activity and activity of major immunoglobulins. In total 120 men aged 30-35 years were included in three groups (30 controls with placebo). Daily doses (50 g) of these products were taken during a month. Positive responses from investigation links of immune system and paraspecific resistance were observed. Immunologic response was significantly higher after lyophilic dairy diet and this indicates that bulgaricum and biostim are products with protective role due to specific influence of bacteria lactic acid.