Low risk of urinary incontinence following prostate brachytherapy in patients with a prior transurethral prostate resection

Int J Radiat Oncol Biol Phys. 1997 Feb 1;37(3):565-9. doi: 10.1016/s0360-3016(96)00570-6.

Abstract

Purpose: To review post implant morbidity in patients with prior transurethral prostate resection (TURP).

Methods and materials: Nineteen patients with stage T1-T2 prostatic carcinoma and prior TURP were treated with I-125 or Pd-103 implantation from 1991 through 1994. Follow-up ranged from 1 to 6 years (median: 3 years). The time from TURP to implantation ranged from 2 months to 15 years (median: 3 years).

Results: Only one patient developed mild urinary stress incontinence, 6 months following his I-125 implant. The actuarial freedom from permanent urinary incontinence at 3 years after implantation was 94%. No patient required urethral dilatation for urethral stricture. Eleven patients were sexually potent prior to implantation. At 3 years after treatment, all patients had maintained potency.

Conclusion: In our experience, there has been remarkably little adverse sequelae following I-125 or Pd-103 implantation in patients with a prior history of TURP.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Brachytherapy / adverse effects*
  • Combined Modality Therapy
  • Follow-Up Studies
  • Humans
  • Iodine Radioisotopes / adverse effects
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Palladium / adverse effects
  • Penile Erection
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / radiotherapy*
  • Prostatic Neoplasms / surgery
  • Radioisotopes / adverse effects
  • Rectum / radiation effects
  • Urinary Incontinence / etiology*

Substances

  • Iodine Radioisotopes
  • Radioisotopes
  • Palladium