Tap (draft) beer and monoamine oxidase inhibitor dietary restrictions

Can J Psychiatry. 1997 Apr;42(3):310-2. doi: 10.1177/070674379704200311.

Abstract

Objective: Traditional monoamine oxidase inhibitors (MAOIs) continue to play an important role in the management of a wide variety of clinical conditions. Accordingly, a practical and safe approach to MAOI dietary restrictions remains an essential component of patient management.

Method: In an effort to refine MAOI dietary recommendations, we report a case of hypertensive crisis following the consumption of a modest amount of tap beer.

Results: A well-documented case report involving tap (draft) beer consumed while on an MAOI supports an earlier study, which recommended that all tap beers be restricted on MAOI diets. The 2 cases were remarkably similar in terms of the offending substance, quantity consumed, and subsequent reaction.

Conclusions: As a result of recent tyramine analyses and 2 well-documented case reports, all tap (draft) beers should now be absolutely restricted on MAOI diets because they represent a very significant risk at modest levels of consumption.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Beer / adverse effects*
  • Bipolar Disorder / drug therapy*
  • Contraindications
  • Depressive Disorder / drug therapy*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Humans
  • Hypertension, Malignant / chemically induced*
  • Hypertension, Malignant / prevention & control
  • Male
  • Monoamine Oxidase Inhibitors / adverse effects*
  • Monoamine Oxidase Inhibitors / therapeutic use
  • Phenelzine / adverse effects*
  • Phenelzine / therapeutic use

Substances

  • Monoamine Oxidase Inhibitors
  • Phenelzine