Abstract
A one-step iodophor skin preparation solution was compared to chlorhexidine gluconate application as a pre-operative skin preparation method in 100 animals undergoing elective ovariohysterectomy. Pre-operative and intra-operative skin cultures demonstrated no difference in antiseptic efficacy. No animal in the study demonstrated signs of systemic infection, and no adverse local effects from either antiseptic were seen. The iodophor solution evaluated (DuraPrep) is a safe and effective pre-operative skin preparation agent in small animal patients undergoing clean surgical procedures.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Infective Agents / adverse effects
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Anti-Infective Agents / standards
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Body Temperature / physiology
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Cat Diseases / physiopathology
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Cat Diseases / prevention & control
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Cats / physiology
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Cats / surgery*
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Chlorhexidine / adverse effects
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Chlorhexidine / standards
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Dog Diseases / physiopathology
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Dog Diseases / prevention & control
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Dogs / physiology
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Dogs / surgery*
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Female
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Heart Rate / physiology
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Hysterectomy / veterinary
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Iodophors / adverse effects
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Iodophors / standards*
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Ovariectomy / veterinary
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Preoperative Care / methods
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Preoperative Care / veterinary*
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Respiration / physiology
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Staphylococcal Infections / physiopathology
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Staphylococcal Infections / prevention & control
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Staphylococcal Infections / veterinary
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Surgical Wound Infection / physiopathology
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Surgical Wound Infection / prevention & control
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Surgical Wound Infection / veterinary
Substances
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Anti-Infective Agents
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Iodophors
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Chlorhexidine