Isolated straight sinus and deep cerebral venous thrombosis: successful treatment with local infusion of urokinase. Case report

C A Holder; D A Bell; A L Lundell; J L Ulmer; S S Glazier

doi:10.3171/jns.1997.86.4.0704

Isolated straight sinus and deep cerebral venous thrombosis: successful treatment with local infusion of urokinase. Case report

J Neurosurg. 1997 Apr;86(4):704-7. doi: 10.3171/jns.1997.86.4.0704.

Authors

C A Holder¹, D A Bell, A L Lundell, J L Ulmer, S S Glazier

Affiliation

¹ Department of Radiology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, USA.

PMID: 9120636
DOI: 10.3171/jns.1997.86.4.0704

Abstract

A 23-year-old woman presented with headache and progressive lethargy. The diagnosis of isolated thrombosis of the straight sinus and of the deep cerebral venous system was established using cranial computerized tomography, magnetic resonance imaging, phase-contrast magnetic resonance venography, and cerebral angiography. Because of the rapid deterioration in the patient's clinical condition, the authors used direct transcatheter infusion of urokinase into the straight sinus. This treatment resulted in a successful outcome.

Publication types

Case Reports

MeSH terms

Adult
Catheterization
Cerebral Angiography
Cerebral Veins* / diagnostic imaging
Cerebral Veins* / pathology
Cranial Sinuses* / diagnostic imaging
Cranial Sinuses* / pathology
Female
Humans
Infusions, Intravenous
Magnetic Resonance Imaging
Phlebography
Subtraction Technique
Thrombophlebitis / diagnosis
Thrombophlebitis / drug therapy*
Tomography, X-Ray Computed
Urokinase-Type Plasminogen Activator / administration & dosage*
Urokinase-Type Plasminogen Activator / therapeutic use

Substances

Urokinase-Type Plasminogen Activator