High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation

Transplant Proc. 1997 Feb-Mar;29(1-2):1081-2. doi: 10.1016/s0041-1345(96)00412-5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cyclosporine / antagonists & inhibitors
  • Cyclosporine / therapeutic use*
  • Graft Rejection / immunology*
  • Graft Rejection / pathology
  • Graft Rejection / prevention & control
  • Heart Transplantation / immunology*
  • Heart Transplantation / pathology
  • Heart Transplantation / physiology
  • Immunosuppressive Agents / antagonists & inhibitors
  • Immunosuppressive Agents / therapeutic use*
  • Interleukin-10 / pharmacology*
  • Male
  • Mice
  • Mice, Inbred C3H
  • Mice, Inbred Strains
  • Myocardial Contraction
  • Spleen / immunology
  • T-Lymphocytes, Cytotoxic / immunology
  • Tacrolimus / antagonists & inhibitors
  • Tacrolimus / therapeutic use*

Substances

  • Immunosuppressive Agents
  • Interleukin-10
  • Cyclosporine
  • Tacrolimus