IL-2 and IL-4 double knock-out mice reject islet allografts: a role for novel T-cell growth factors?

Transplant Proc. 1997 Feb-Mar;29(1-2):1083-4. doi: 10.1016/s0041-1345(96)00413-7.
No abstract available

MeSH terms

  • Animals
  • Antibodies / therapeutic use
  • CD3 Complex / immunology
  • Diabetes Mellitus, Experimental / surgery
  • Graft Rejection / immunology*
  • Graft Rejection / pathology
  • Graft Survival*
  • Immunosuppression Therapy / methods
  • Immunosuppressive Agents / therapeutic use
  • Interleukin-2 / genetics
  • Interleukin-2 / immunology*
  • Interleukin-4 / genetics
  • Interleukin-4 / immunology*
  • Islets of Langerhans Transplantation / immunology*
  • Islets of Langerhans Transplantation / pathology
  • Lymphocyte Activation
  • Mice
  • Mice, Inbred DBA
  • Mice, Knockout
  • Polyenes / therapeutic use
  • Sirolimus
  • Spleen / immunology
  • T-Lymphocytes / immunology*
  • Transplantation, Homologous

Substances

  • Antibodies
  • CD3 Complex
  • Immunosuppressive Agents
  • Interleukin-2
  • Polyenes
  • Interleukin-4
  • Sirolimus