Unusual polyp-like structures in lobular panniculitis of a patient with Behçet's disease

Am J Dermatopathol. 1997 Apr;19(2):185-8. doi: 10.1097/00000372-199704000-00014.

Abstract

Unusual histopathologic structures were observed in lobular panniculitis of a patient with Behçet's disease. These were polyp-like in shape and protruded into cavities made of lysed fat cells. Various stages of development were observed. To determine the origin of cells making up these structures, we applied various histochemical and immunohistochemical techniques and found the cells to be histiocytes (macrophages) engaged in phagocytizing degenerated fat cells and cell membranes which had formed into membranocystic lesions.

Publication types

  • Case Reports

MeSH terms

  • Adipose Tissue / pathology
  • Aged
  • Antigens, CD / analysis
  • Antigens, Differentiation, Myelomonocytic / analysis
  • Behcet Syndrome / pathology*
  • Cell Lineage
  • Cell Membrane / ultrastructure
  • Histiocytes / pathology
  • Histocytochemistry
  • Humans
  • Hyaluronic Acid / analysis
  • Immunohistochemistry
  • Macrophages / pathology
  • Male
  • Muramidase / analysis
  • Panniculitis / pathology*
  • Phagocytosis
  • alpha 1-Antichymotrypsin / analysis

Substances

  • Antigens, CD
  • Antigens, Differentiation, Myelomonocytic
  • CD68 antigen, human
  • alpha 1-Antichymotrypsin
  • Hyaluronic Acid
  • Muramidase