[E wave deceleration time predicts left ventricular telediastolic pressure in acute myocardial infarction in patients with systolic dysfunction]

Rev Esp Cardiol. 1997 Mar;50(3):173-8. doi: 10.1016/s0300-8932(97)73200-7.
[Article in Spanish]

Abstract

Objectives: Left ventricular end-diastolic pressure (LVEDP) is a useful parameter for the management of postinfarction patients. As the current methods of estimating LVEDP are invasive, the existence of non-invasive methods would be of great practical value. This study investigates the relation between LVEDP and Doppler parameters such as E wave deceleration time (EDT) and E/A ratio, at one month following an acute myocardial infarction.

Methods: Eighty-nine patients with a first acute myocardial infarction treated with thrombolytic agents were studied. Doppler-echocardiography at 29 +/- 3 days and cardiac catheterization at 30 +/- 4 days postinfarction were performed. According to the ejection fraction (EF), the patients were divided into group 1 (n = 17) with EF < 45%, and group 2 (n = 72) with EF > 45%.

Results: Overall, the E/A ratio showed a weak correlation with LVEDP (r = 0.32; p = 0.007), and EDT did not correlate with LVEDP. When patients from group 2 were analyzed, no correlation was found between LVEDP and either E/A or EDT. However, in patients from group 1, LVEDP strongly correlated with both EDT (r = -0.83; p = 0.00001) and E/A (r = 0.70; p = 0.003). Moreover, the sensitivity and specificity of an EDT of less than 150 ms in predicting a LVEDP > 20 mmHg was 100%.

Conclusions: We conclude that at the first month after a myocardial infarction EDT provides a non-invasive and useful parameter for estimating LVEDP in patients with systolic dysfunction.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Data Interpretation, Statistical
  • Diastole
  • Echocardiography, Doppler*
  • Female
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / physiopathology*
  • Time Factors
  • Ventricular Dysfunction, Left / physiopathology
  • Ventricular Function, Left*