Relationship between the development of blindness in Churg-Strauss syndrome and anti-myeloperoxidase antibodies

N Sutcliffe; V Morris; B Gomperts; D J Brazier; D A Isenberg; G Cambridge

doi:10.1093/rheumatology/36.2.273

Relationship between the development of blindness in Churg-Strauss syndrome and anti-myeloperoxidase antibodies

Br J Rheumatol. 1997 Feb;36(2):273-5. doi: 10.1093/rheumatology/36.2.273.

Authors

N Sutcliffe¹, V Morris, B Gomperts, D J Brazier, D A Isenberg, G Cambridge

Affiliation

¹ Bloomsbury Rheumatology Unit/Division of Rheumatology, Department of Medicine, University College London.

PMID: 9133946
DOI: 10.1093/rheumatology/36.2.273

Abstract

Occular involvement is infrequent and blindness rare in Churg-Strauss syndrome. We describe a patient with Churg-Strauss syndrome who presented with blindness. This was associated with the appearance of circulating autoantibodies to myeloperoxidase.

Publication types

Case Reports

MeSH terms

Autoantibodies / analysis*
Biomarkers
Blindness / enzymology
Blindness / etiology*
Churg-Strauss Syndrome / complications*
Churg-Strauss Syndrome / enzymology
Eosinophils / physiology
Fundus Oculi
Humans
Leukocyte Count
Male
Middle Aged
Peroxidase / immunology*

Substances

Autoantibodies
Biomarkers
Peroxidase