Drug-induced antisynthetase syndrome

Postgrad Med J. 1997 Mar;73(857):165-6. doi: 10.1136/pgmj.73.857.165.

Abstract

We present a case of antisynthetase syndrome whose predominant feature was fibrosing alveolitis and which may have been drug-induced. This responded well to steroids and cyclophosphamide.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiotensin II*
  • Angiotensin Receptor Antagonists*
  • Anti-Inflammatory Agents / therapeutic use
  • Arthritis / chemically induced*
  • Arthritis / drug therapy
  • Arthritis / immunology
  • Autoantibodies / blood
  • Autoimmune Diseases / blood
  • Autoimmune Diseases / chemically induced*
  • Autoimmune Diseases / drug therapy
  • Cytoskeleton / immunology
  • Humans
  • Male
  • Prednisolone / therapeutic use
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / drug therapy
  • Pulmonary Fibrosis / immunology
  • Raynaud Disease / chemically induced*
  • Raynaud Disease / drug therapy
  • Raynaud Disease / immunology
  • Skin Diseases / chemically induced*
  • Skin Diseases / drug therapy
  • Skin Diseases / immunology
  • Syndrome
  • Tetrazoles / adverse effects*
  • Valine / adverse effects
  • Valine / analogs & derivatives*
  • Valsartan

Substances

  • Angiotensin Receptor Antagonists
  • Anti-Inflammatory Agents
  • Autoantibodies
  • Tetrazoles
  • Angiotensin II
  • Valsartan
  • Prednisolone
  • Valine